San Francisco 49ers vs Arizona Cardinals Preview
The kickoff for this week 4 matchup between the Cardinals and 49ers takes place at 4:25 ET at Levi’s Stadium. FOX will be carrying the television coverage for this ARI vs. SF shodown.
In this matchup of NFC West division rivals, the 49ers are listed as 14 point home favorites. Can they secure a home and cover the spread? Check out BetCoco for San Francisco 49ers – Arizona Cardinals odds
San Francisco 49ers vs Arizona Cardinals Head-to-Head and Key Stats
When looking back at the head to head matchups last season, the 49ers and Cardinals faced off two times, with the 49ers going 2-0. The two teams averaged a combined 49.5 points per game leading to an over/under record of 2-0. Against the spread, the 49ers went 2-0. Offensively, the 49ers averaged 349 yards per game in the head-to-head matchups compared to the Cardinals at 284.5 yards.
The last five times that the 49ers have hosted the Cardinals, they have an above .500 record at 3-2. In the last three games as the favorite against the Cardinals, the 49ers have put together a 2-1 vs. the spread.
San Francisco 49ers vs Arizona Cardinals Prediction
In their game against the 49ers, the Cardinals will aim to improve their 1-2 record. This positions them 4th in the NFC-West and 13th in the NFC. The Cardinals have a 3-0 record against the spread this season. So far this season, their average scoring margin is +1.7. So far this season, Arizona games are 12th in total points. They come in with an over/under record of 2-1, with an average over/under line for their games set at 40.2 points.
On the offensive side of the ball, the Cardinals currently hold an average of 24 points per game, which places them at 12th in the NFL. Heading into this week’s matchup with the 49ers, the Cardinals defense has given up an average of 22.3 points per game. They are currently 13th in quarterback hits and have allowed an average of 367.7 yards per contest.
Taking a glance at the NFC-West standings, the 49ers are 1st with a record of 3-0. Within the NFC, San Francisco is currently in 1st place as they enter week 4. With a scoring margin of +16, the 49ers’ have achieved an ATS record of 2-0-1 so far. So far this season, San Francisco games are 14th in total points. Their over/under record is 1-2 and the average over/under line for their games is 43.3 points.
On offense, the 49ers are averaging 30 points per game, putting them 3rd in the NFL. On the defensive side of the ball, the 49ers give up an average of 205.3 passing yards and 53.0 rushing yards per game. Looking at their sack numbers, San Francisco is currently ranked 6th in the league. So far, they are giving up 14 points per game and 258.3 yards.
With a 14-point advantage on the spread, our projections favor the 49ers to secure a 21-17 victory. Our analytics have assigned San Francisco a 62% chance of defeating the Cardinals.
San Francisco 49ers vs Arizona Cardinals Betting Tips
- Take the 49ers on the moneyline
- On the spread, we like Cardinals (+14)
- Our NFL model projects 38 points, and we suggest taking the under
San Francisco 49ers Injury Report
- Deebo Samuel – Ribs/knee (Questionable)
- Brandon Aiyuk – Shoulder (Questionable)
- Samuel Womack III – Knee (Out)
- Danny Gray – Shoulder (Out)
- Darrell Luter Jr. – Knee (Out)
- Ambry Thomas – Knee (Questionable)
- Robert Beal Jr. – Hamstring (Out)
- Cameron Latu – Knee (Out)
- Demetrius Flannigan-Fowles – Ankle (Questionable)
- Jauan Jennings – Shin (Questionable)
- Dre Greenlaw – Ankle (Questionable)
Arizona Cardinals Injury Report
- Budda Baker – Hamstring (Out)
- Pat Elflein – Hip (Out)
- Marlon Mack – Achilles (Out)
- Carlos Watkins – Bicep (Out)
- Josh Woods – Ankle (Questionable)
- Rashad Fenton – Undisclosed (Out)
- Kyler Murray – Knee (Out)
- L.J. Collier – Bicep (Out)
- Dennis Daley – Ankle (Out)
- Krys Barnes – Finger (Questionable)
- Myjai Sanders – Hand (Out)
- Hayden Howerton – Undisclosed (Out)
- Garrett Williams – Knee (Out)
- Jon Gaines II – Knee (Out)
- Matt Hembrough – Back (Out)
- James Conner – Back (Probable)
- Jonathan Ledbetter – Finger (Questionable)
- Marquise Brown – Thumb (Questionable)
- Keaontay Ingram – Neck (Questionable)
